Historical clue formulations

• "Science may have found a cure for most evils; but it has found no remedy for the worst of them all - the ___ of human beings": Helen Keller — 2019-04-20
• Interest's opposite — 2018-03-18
• Opposite of drive — 2017-10-27
• It may elicit a shrug — 2014-10-24
• It might elicit a shrug — 2013-04-19
• Lack of interest — 2012-08-13
• Lack of interest — 2009-01-05
• What two palms up may indicate — 2006-04-23
• Voters' problem — 2004-10-08
• Shrug-of-the-shoulders feeling — 2003-11-26
• Burnout consequence — 2003-03-22
• Voters' problem — 2002-02-07
• What a shrug may indicate — 2001-09-06
• Coolness — 1997-12-11