Historical clue formulations

• O.C.D. fighter, maybe — 2018-03-09
• Mood-enhancing drug — 2016-12-06
• Paxil alternative — 2015-03-06
• Antidepressant brand — 2012-12-12
• Disposition pick-me-up — 2008-07-02
• Mood lifter — 2007-09-09