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Other answers seen for this clue

• RILE4 letters

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  Appeared in 5 New York Times Crosswords between June 2001 and December 2019.
• ANNOY5 letters

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  Appeared in 3 New York Times Crosswords between May 2003 and November 2022.
• ACCESS6 letters

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  Appeared in 3 New York Times Crosswords between August 1996 and July 2015.
• REACH5 letters

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  Appeared in 3 New York Times Crosswords between January 2003 and March 2008.
• ATTEND6 letters

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  Appeared in 1 New York Times Crossword: Friday, December 5, 2025.
• IRRITATE8 letters

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  Appeared in 1 New York Times Crossword: Sunday, July 6, 2014.
• NETTLE6 letters

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  Appeared in 1 New York Times Crossword: Saturday, October 1, 2011.

• Annoy

  New York Times · Friday, April 10, 2026 · 3 letters

• Peeve

  New York Times · Thursday, March 19, 2026 · 3 letters

• Vex

  New York Times · Sunday, October 5, 2025 · 3 letters

• Tick off

  New York Times · Sunday, August 4, 2024 · 3 letters

• Bother

  New York Times · Wednesday, July 3, 2024 · 3 letters

• Rub the wrong way

  New York Times · Monday, February 28, 2022 · 3 letters

• Bug

  New York Times · Saturday, April 24, 2021 · 3 letters

• Put out

  New York Times · Friday, October 23, 2020 · 3 letters

• Cause to groan, maybe

  New York Times · Saturday, April 13, 2019 · 3 letters

• Rankle

  New York Times · Wednesday, February 20, 2019 · 3 letters

More clues from this crossword

• 43-Across Pro device
• 44-Across ___ out a win
• 45-Across Bond alternatives
• 46-Down Film production environment for an intimate scene, perhaps
• 47-Across "... ___ no one ever"
• 48-Down Digital security credential
• 50-Across Edge jump in figure skating
• 51-Down Telegram and Simple Dialer, for two
• 52-Across Scenes on Black Friday
• 53-Down Cannellini, e.g.
• 54-Down Organ-related item in a wallet
• 55-Down Perfect place