Serious suffering Crossword Clue

• Torment

  New York Times · Friday, June 26, 2026 · 5 letters

• Extreme pain

  New York Times · Sunday, March 2, 2025 · 5 letters

• Ecstasy's opposite

  New York Times · Tuesday, February 27, 2024 · 5 letters

• "The thrill of victory … and the ___ of defeat" ("Wide World of Sports" catchphrase)

  New York Times · Sunday, August 27, 2023 · 5 letters

• "The ___ and the Ecstasy" (biographical novel about Michelangelo)

  New York Times · Tuesday, May 30, 2023 · 5 letters

• Intense suffering

  New York Times · Tuesday, March 14, 2023 · 5 letters

• Sitting next to a constantly crying baby on a cross-country flight, maybe

  New York Times · Friday, June 12, 2020 · 5 letters

• What waiting for overdue results can be

  New York Times · Tuesday, March 27, 2018 · 5 letters

• Having one's wisdom teeth pulled, e.g.

  New York Times · Wednesday, May 24, 2017 · 5 letters

• Excruciating pain

  New York Times · Monday, February 20, 2017 · 5 letters

More clues from this crossword

• 46-Down Docking spots
• 47-Down Spanish for "foolish"
• 48-Across Some I.C.U. workers
• 49-Across Alternative to Hinge or Bumble
• 50-Across On which Maya Rudolph has played Kamala Harris, in brief
• 51-Across Enjoys a lazy Sunday, say
• 53-Across 2020 nonfiction best seller subtitled "The Origins of Our Discontents"
• 54-Across Over or under
• 54-Down "Seriously …"
• 55-Down Sooner State city
• 56-Down Béret bearer
• 57-Across … a volume on vapor dynamics?